Albendazole Tablet 600mg
Composition:
Albendazole ……………600 mg
Excipients q.s. …………1 bolus.
Indications:
Prevention and treatment of gastrointestinal and pulmonary strongyloses, cestodoses, fascioliasis and dicrocoelioses. albendazole 600 is ovicidal and larvicidal. it is active in particular on encysted larvae of respiratory and digestive strongyles.
Contraindications:
Hypersensitive to albendazole or any components of alben600
Dosage And Administration:
Orally:
Sheep ,goat and cattle:
1bolus per 50kg-80kg of body weight
For liver-fluke: 2bolus per 50kg-80kg of body weight
Side Effects:
Dosage up to 5times the therapeutic dose have been given to farm animals without producing significant side effects.under experimental conditions the toxic effect appears to be associated with anorexia and nausea .the drug is not teratogenic when tested using normal laboratory criteria.
Precautions general:animals being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required.oral or intravenous corticosteroid should be considered to prevent cerebral hypertensive episodes during the first week of anticysticeral therapy
Cysticerosis may, in rare cases ,involve the retina,before initiating therapy for neurocysticercosis , the animal should be examined for the presence of retinal lesions, if such lesions are visualized , the need for anticysticeral therapy should be weighed against the possibility of retinal damage caused by albendazole induced changes to the retinal lesions.
Warning :
Cattle and calves must not be slaughter within 10days following last treatment and the milk should not used before 3days of last treatment
Precaution :
Do not administer to female cattle druing first 45days of pregnancy or for 45days after removal of bulls,consult your veterinarian for assistance in the diagnosis,treatment and control parasitism.
Interactions:
Albendazole has been shown to induce liver enzymes of the cytochrome p-150 system responsible for its own metabolism.therefore ,there is a theoretical risk of interaction with theophylline,anticonvuisants,oral contraceptives and oral hypoglycaemics.therefore care should be exercised druing the introduction of albendazole in animals receiving the above groups of compounds .
Cimetidine and praziquantel have been reported to increase the plasma level of the albendazole active metabolite.
Overdosage And Treatment:
No effects were reported,however,symptomatic and gegeral supportive measures are recommended.
Withdrawal times:
Meat : 10days
Milk : 3 days.
Storage:
Store in a cool, dry and dark place below 30°c.
Keep out of reach of children.
Shelf Life:
4 years
Package: blister packing of 12×5 bolus