High Quality Tilmicosin Phosphate - Florfenicol Sodium Succinate – Jizhong

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High Quality Tilmicosin Phosphate - Florfenicol Sodium Succinate – Jizhong Detail:

Florfenicol Sodium Succinate
Product name : Florfenicol sodium succinate

Chemical properties :
White or white-like crystalline powder, odorless and tasteless, when the air humidity is high deliquescent This product is slightly soluble in acetone, ethanol, easy soluble in water, containing florfenicol sodium succinate is not less than 95% .

Product Feature:
1. Florfenicol sodium succinate make the Florfenicol solubility to 300mg/ml and added  400 times.
2. Florfenicol sodium succinate make the Florfenicol the dissolution rate 200 times faster, without any co-solvent, soluble instant in water
3. Florfenicol sodium succinate is Florfenicol derivatives, into the body by the enzyme catalyzed efficiently into florfenicol and effective blood concentration of long duration.
4. It does not require an organic solvent participation can be used in clinical administration, to avoid the side effects of using an organic solvent (to improve the safety of the drug, reduce the residual).

Pharmacology :
This product is Florfenicol derivatives, in accordance with the principle of the prodrug design made it a variety of gram-positive and gram-negative bacteria and have a role in mycoplasma .
The antibacterial mechanism is with the 50S ribosomal subunit , and inhibits a key enzyme required for protein synthesis – the peptidyl transferase, which would specifically prevent the aminoacyl-tRNA binding to receptors on the ribosome inhibitory peptide chain extended leaving the bacterial protein can not be synthesized . This product will not only increase its water-soluble, and oral and injection process in vivo loss, after enzyme metabolism in the body decomposition in esters and florfenicol ester overcome bacterial resistance. Florfenicol targeting, play a very effective drugs acting on the organism, the amount is small, fast effect, a long half-life, high plasma concentration, a longer period of time to maintain the plasma concentration. Mainly by the kidneys excretion.
 
Indications
Used in chicken E. coli disease and Serositis and fish kill salmon Aeromonas, Vibrio anguillarum for sensitive bacteria in cattle, pigs, chicken intestinal infection and mycoplasma caused by chronic respiratorydisease.
 
Dosage
Poultry: mixed drink of 100L water 3.5-4g,   livestock, per kilogram of body weight 20-25mg ,once per day and use three days. IM: chickens, pigs, cattle and the amount of time per kilogram of body weight of 15-20mg ,every 48h per time . use two times .

 


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    5 Stars By Johnny from Pakistan - 2018.06.12 16:22
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